Course Description

ΥΠ1 - Biology - Physiology
Code:	ΥΠ1
Title Course:	Biology - Physiology
Semester:	1st
Category:	REQUIRED
Lecture hours:	3
Instructor:	Xanthou (BRFAA), Anastasiadou (BRFAA)
Course web page:	http://eclass.uoa.gr/courses/D437/
Course Description:
The course aims to provide a comprehensive introduction to the development, differentiation, reproduction and functioning of the structural unit of living beings, the cell. Emphasis will be placed on the transfer of genetic information, its relationship to normal cell function and the importance of its disturbance in the process of pathogenesis. The organization of cell in systems and the ways systems communicate will help in the understanding of the importance of the networks created in the body for normal functioning. The analysis of the functioning rules of the systems will explain the contribution of systems modelling to the understanding of the pathogenesis process and to designing therapeutic approaches. The reference to the principles of genetics and issues relating to the detection of genetic information will raise the social dimension of the current research activity including bioinformatics. The basic biological unit: the cell (organization of cells. cytoskeleton, cell organelles, structure and function, biofilms, receptors). Structural components of the cell: proteins (structure, function, regulation, analysis, predicition). Cell division - Cell cycle. Cellular communication (biochemical / molecular organization of communication between different functions, examples of disruption to the smooth interaction). Genetic Information: DNA (Deoxyrivonucleic acids, genes, chromosomes, genomes). From DNA, to RNA, to the synthesis of proteins. Genetic Code (Transcription, Translation, Analysis and organization of sequences). Genetic engineering: . Sequences-homology - families – protein interactions. Enzymes. Recombinant proteins (antibodies - vaccines). From cell to systems (Principles of organization and operation of systems). Organisation of specific systems, such as cardiovascular and endocrine, focusing on mechanisms of synergy, e.g. signal transduction pathways. Physiology of the Nervous System (principles of cellular and molecular neurobiology and examples of functions such as learning and memory) differentiation (stem cells, cell types, tissues, cell therapies). Evolution (phylogenetic trees). Principles of human genetics. Molecular basis of disease (Pathogenesis of common diseases such as cancer, diabetes). [Previous page]